Phosphoramidate-peptide synthesis by solution- and solid-phase Staudinger-phosphite reactions.

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Serwa, Remigiusz A; Swiecicki, Jean-Marie; Homann, Denise; Hackenberger, Christian P R;
(2010)
  • Publisher: Wiley
  • Related identifiers: doi: 10.1002/psc.1236
  • Subject: [CHIM.ORGA]Chemical Sciences/Organic chemistry | [ CHIM.ORGA ] Chemical Sciences/Organic chemistry

International audience; The chemoselective incorporation of phosphoramidate moieties into peptides by a Staudinger-phosphite reaction of azides can be performed in many solvents, including water. In this report, we present two strategies for an efficient synthesis of ph... View more
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