Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle

Article, Other literature type English OPEN
Castro, Gabriela S. de; Simoes, Estefania; Lima, Joanna D.C.C.; Ortiz-Silva, Milene; Festuccia, William T.; Tokeshi, Flávio; Alcântara, Paulo S.; Otoch, José P.; Coletti, Dario; Seelaender, Marilia;
(2019)

Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between protein synthesis and degradation, which is related with poor prognosis and compromised quality of life. Dysfunctional mitochondria are associated with l... View more
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