Genetic diversity is a predictor of mortality in humans

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Bihlmeyer, Nathan A; Brody, Jennifer A; Smith, Albert Vernon; Lunetta, Kathryn L; Nalls, Mike; Smith, Jennifer A; Tanaka, Toshiko; Davies, Gail; Yu, Lei; Mirza, Saira Saeed; Teumer, Alexander; Coresh, Josef; Pankow, James S; Franceschini, Nora; Scaria, Anish; Oshima, Junko; Psaty, Bruce M; Gudnason, Vilmundur; Eiriksdottir, Gudny; Harris, Tamara B; Li, Hanyue; Karasik, David; Kiel, Douglas P; Garcia, Melissa; Liu, Yongmei; Faul, Jessica D; Kardia, Sharon LR; Zhao, Wei; Ferrucci, Luigi; Allerhand, Michael; ... view all 52 authors
(2014)

Background: It has been well-established, both by population genetics theory and direct observation in many organisms, that increased genetic diversity provides a survival advantage. However, given the limitations of both sample size and genome-wide metrics, this hypoth... View more