Antibody and Cytokine Responses of Koalas (Phascolarctos cinereus) Vaccinated with Recombinant Chlamydial Major Outer Membrane Protein (MOMP) with Two Different Adjuvants.

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Shahneaz Ali Khan ; Marion Desclozeaux ; Courtney Waugh ; Jon Hanger ; Jo Loader ; Volker Gerdts ; Andrew Potter ; Adam Polkinghorne ; Kenneth Beagley ; Peter Timms
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 11, issue 5 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC4878773, doi: 10.1371/journal.pone.0156094
  • Subject: Immune System Proteins | Research Article | Bacteria | Vaccines | Infectious Diseases | Preventive Medicine | Immunoassays | Vaccination and Immunization | Immunologic Adjuvants | Immune Response | Proteins | Public and Occupational Health | Enzyme-Linked Immunoassays | Antibodies | Immunology | Chlamydia Infection | Biology and Life Sciences | Immune Physiology | Chlamydia | Research and Analysis Methods | Physiology | Medicine | Immunologic Techniques | Sexually Transmitted Diseases | Q | R | Biochemistry | Science | Organisms | Medicine and Health Sciences

Developing a vaccine against Chlamydia is key to combating widespread mortalities and morbidities associated with this infection in koalas (Phascolarctos cinereus). In previous studies, we have shown that two or three doses of a Recombinant Major Outer Membrane Protein ... View more
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