publication . Article . 1986

Recainam, A potent new antiarrhythmic agent: Effects on complex ventricular arrhythmias

Anastasiou-Nana, Maria I.; Anderson, Jeffrey L.; Hampton, Edward M.; Nanas, John N.; Heath, Barbara M.;
Open Access English
  • Published: 01 Aug 1986 Journal: Journal of the American College of Cardiology, issue 2, pages 427-435 (issn: 07351097, Copyright policy)
  • Publisher: American College of Cardiology Foundation. Published by Elsevier Inc.
Abstract
The antiarrhythmic efficacy and safety of intravenous recainam, a newly synthesized compound displaying potent class I antiarrhythmic activity, were tested in 10 hospitalized patients with frequent (>30/h) complex ventricular ectopic beats. There were seven men and three women of average age 57 years (range 21 to 74); five had ischemic heart disease, three had cardiomyopathy and two had valvular heart disease. Recainam was given as a 3.0 mg/kg per 40 min loading infusion followed by a 0.9 mg/kg per h maintenance infusion over a 24 hour observation period. Arrhythmia response was assessed both in the short term (comparing 2 hours before and 1 hour after drug load...
Subjects
free text keywords: Cardiology and Cardiovascular Medicine, Anesthesia, Cardiomyopathy, medicine.disease, medicine, Diabetes mellitus, Drug, media_common.quotation_subject, media_common, Antiarrhythmic agent, medicine.medical_treatment, valvular heart disease, Chemotherapy, Premature ventricular complexes, Ventricular Ectopic Beats, Cardiology, medicine.medical_specialty, Internal medicine, business.industry, business
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