Synthesis and in-vitro cytotoxicity of dendrimer cytostatic conjugates

Doctoral thesis German OPEN
Scutaru, Ana Maria;
  • Publisher: Freie Universität Berlin Universitätsbibliothek, Garystr. 39, 14195 Berlin
  • Subject: 615 Pharmakologie, Therapie | dendrimers-drug-conjugates | in-vitro cytotoxicity | 547 Organische Chemie | melphalan | 615 Pharmacology and therapeutics | 547 Organic chemistry | Bendamustine
    • ddc: ddc:615 | ddc:547

Bendamustine and melphalan are nitrogen mustard derivatives from the group of alkylating agents and are used for the treatment of various cancers such as chronic lymphocytic leukemia (CLL) or breast cancer. However their use is limited by numerous side effects. Therefor... View more
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