Subject: Research Article | Science & Technology | Internal medicine | RC31-1245 | Article Subject
The goal of this study was to determine and compare the effects of the secretome of mesenchymal stem cells (MSCs) isolated from human bone-marrow (BMSCs) and the Wharton jelly surrounding the vein and arteries of the umbilical cord (human umbilical cord perivascular cel... View more
 J. G. Emsley, B. D. Mitchell, G. Kempermann, and J. D. Macklis, “Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells,” Progress in Neurobiology, vol. 75, no. 5, pp. 321-341, 2005.
 M. Dominici, K. Le Blanc, I. Mueller et al., “Minimal criteria for denfiing multipotent mesenchymal stromal cells. The International Society for Cellular eThrapy position statement,” Cytotherapy, vol. 8, no. 4, pp. 315-317, 2006.
 F. G. Teixeira, M. M. Carvalho, N. Sousa, and A. J. Salgado, “Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?” Cellular and Molecular Life Sciences, vol. 70, pp. 3871-3882, 2013.
 M. M. Carvalho, F. G. Teixeira, R. L. Reis, N. Sousa, and A. J. Salgado, “Mesenchymal stem cells in the umbilical cord: phenotypic characterization, secretome and applications in central nervous system regenerative medicine,” Current Stem Cell Research and eThrapy , vol. 6, no. 3, pp. 221-228, 2011.
 H. Ohtaki, J. H. Ylostalo, J. E. Foraker et al., “Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inaflmmatory/immune responses,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 38, pp. 14638-14643, 2008.
 A. C. Hirko, R. Dallasen, S. Jomura, and Y. Xu, “Modulation of inflammatory responses aeftr global ischemia by transplanted umbilical cord matrix stem cells,” Stem Cells, vol. 26, no. 11, pp. 2893-2901, 2008.
 D. Cizkova, J. Rosocha, I. Vanicky, S. Jergova, and M. Cizek, “Transplants of human mesenchymal stem cells improve functional recovery aeftr spinal cord injury in the rat,” Cellular and Molecular Neurobiology, vol. 26, pp. 1167-1180, 2006.
 H. L. Kyung, H. Suh-Kim, S. C. Ji et al., “Human mesenchymal stem cell transplantation promotes functional recovery following acute spinal cord injury in rats,” Acta Neurobiologiae Experimentalis, vol. 67, no. 1, pp. 13-22, 2007.
 G. Bouchez, L. Sensebe´, P. Vourc'h et al., “Partial recovery of dopaminergic pathway aeftr graft of adult mesenchymal stem cells in a rat model of Parkinson's disease,” Neurochemistry International, vol. 52, no. 7, pp. 1332-1342, 2008.
 M. L. Weiss, S. Medicetty, A. R. Bledsoe et al., “Human umbilical cord matrix stem cells: preliminary characterization and eefct of transplantation in a rodent model of Parkinson's disease,” Stem Cells, vol. 24, no. 3, pp. 781-792, 2006.