Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer.

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Chang, Keejong; Qian, Jin; Jiang, MeiSheng; Liu, Yi-Hsin; Wu, Ming-Che; Chen, Chi-Dar; Lai, Chao-Kuen; Lo, Hsin-Lung; Hsiao, Chin-Ton; Brown, Lucy; Bolen, James; Huang, Hsiao-I; Ho, Pei-Yu; Shih, Ping Yao; Yao, Chen-Wen; Lin, Wey-Jinq; Chen, Chung-Hsi; Wu, Fang-Yi; Lin, Yi-Jen; Xu, Jing; Wang, Ken;

<p>Abstract</p> <p>Background</p> <p>Transgenic animals have become valuable tools for both research and applied purposes. The current method of gene transfer, microinjection, which is widely used in transgenic mouse production, has only had limited success in producing... View more
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