Surface Phosphatidylserine Is Responsible for the Internalization on Microvesicles Derived from Hypoxia-Induced Human Bone Marrow Mesenchymal Stem Cells into Human Endothelial Cells

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Wei, Xiaojuan; Liu, Chaozhong; Wang, Hengxiang; Wang, Lisheng; Xiao, Fengjun; Guo, Zikuan; Zhang, Hongchao;
(2016)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 11,issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0147360, pmc: PMC4726621
  • Subject: Immune System Proteins | Endothelial Cells | Research Article | Anatomy | Apoptosis | Cell Processes | Spectrophotometry | Genetics | Biological Tissue | Proteins | Spectrum Analysis Techniques | Flow Cytometry | Antibodies | Light Microscopy | Embryology | Umbilical Cord | Immunology | Cellular Types | Stem Cells | Biology and Life Sciences | Non-coding RNA | RNA | Cell Death | Immune Physiology | Developmental Biology | Research and Analysis Methods | Physiology | Epithelial Cells | Medicine | Animal Cells | Nucleic acids | Small interfering RNAs | Q | R | Cell Biology | Gene regulation | Confocal Microscopy | Mesenchymal Stem Cells | Science | Biochemistry | Cytophotometry | Epithelium | Microscopy | Medicine and Health Sciences | Gene expression | Monoclonal Antibodies
    mesheuropmc: embryonic structures

Background Previous data have proven that microvesicles derived from hypoxia-induced mesenchymal stem cells (MSC-MVs) can be internalized into endothelial cells, enhancing their proliferation and vessel structure formation and promoting in vivo angiogenesis. However, th... View more
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