Mapping the drivers of within-host pathogen evolution using massive data sets

Article, Preprint OPEN
Palmer, Duncan S.; Turner, Isaac; Fidler, Sarah; Frater, John; Goulder, Philip; Goedhals, Dominique; Huang, Kuan-Hsiang; Oxenius, Annette; Phillips, Rodney; Van Vuuren, Cloete; Mclean, Angela;

Differences among hosts, resulting from genetic variation in the immune system or heterogeneity in drug treatment, can impact within-host pathogen evolution. Identifying such interactions can potentially be achieved through genetic association studies. However, extensiv... View more