Molecular Dynamics Investigation of Cl− and Water Transport through a Eukaryotic CLC Transporter

Article, Other literature type English OPEN
Cheng, Mary Hongying; Coalson, Rob D.;

Early crystal structures of prokaryotic CLC proteins identified three Cl– binding sites: internal (Sint), central (Scen), and external (Sext). A conserved external GLU (GLUex) residue acts as a gate competing for Sext. Recently, the first crystal structure of a eukaryot... View more
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