Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy

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Rbah-Vidal, Latifa; Vidal, Aurélien; Billaud, Emilie,; Besse, Sophie; Ranchon-Cole, Isabelle; Mishellany, Florence; Perrot, Yann; Maigne, Lydia; Moins, Nicole; Guerquin-Kern, Jean-Luc; Degoul, Françoise; Chezal, Jean-Michel; Auzeloux, Philippe; Miot-Noirault, Elisabeth;
  • Publisher: Springer Verlag (Germany)
  • Journal: Neoplasia: An International Journal for Oncology Research,volume 19,issue 1,pages17-27 (issn: 1476-5586, eissn: 1522-8002)
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  • Related identifiers: doi: 10.1016/j.neo.2016.11.001
  • Subject: [SDV.CAN]Life Sciences [q-bio]/Cancer | RC254-282 | [ SDV.CAN ] Life Sciences [q-bio]/Cancer | Neoplasms. Tumors. Oncology. Including cancer and carcinogens

International audience; PURPOSE: This work reports, in melanoma models, the theranostic potential of ICF15002 as a single fluorinated and iodinated melanin-targeting compound. METHODS: Studies were conducted in the murine syngeneic B16BL6 model and in the A375 and SK-ME... View more
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