Effects of icotinib with and without radiation therapy on patients with EGFR mutant non-small cell lung cancer and brain metastases

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Fan, Yun ; Xu, Yanjun ; Gong, Lei ; Fang, luo ; Lu, Hongyang ; Qin, Jing ; Han, Na ; Xie, Fajun ; Qiu, Guoqin ; Huang, Zhiyu (2017)
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports, volume 7 (issn: 2045-2322, eissn: 2045-2322)
  • Related identifiers: pmc: PMC5362911, doi: 10.1038/srep45193
  • Subject: Article

EGFR-TKIs and radiation therapy (RT) are the principal treatment for patients with brain metastases (BM) and EGFR mutant NSCLC. However, the optimal use of brain RT for patients with asymptomatic BM remains undefined. A total of 152 patients were identified. 58 patients... View more
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