Effects of acetazolamide on the micro- and macro-vascular cerebral hemodynamics: A diffuse optical and transcranial doppler ultrasound study

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Zirak P. ; Delgado-Mederos R. ; Marti-Fabregas J. ; Durduran T. (2010)
  • Publisher: Optical Society of America
  • Journal: Biomedical Optics Express, volume 1, issue 5, pages 1,443-1,459 (issn: 2156-7085, eissn: 2156-7085)
  • Related identifiers: doi: 10.1364/BOE.1.001443, pmc: PMC3018112
  • Subject: (170.3660) Light propagation in tissues | (170.3890) Medical optics instrumentation | Neuroscience and Brain Imaging | (170.7170) Ultrasound | (170.6480) Spectroscopy, speckle | (290.4210) Multiple scattering
    mesheuropmc: cardiovascular system

Acetazolamide (ACZ) was used to stimulate the cerebral vasculature on ten healthy volunteers to assess the cerebral vasomotor reactivity (CVR). We have combined near infrared spectroscopy (NIRS), diffuse correlation spectroscopy (DCS) and transcranial Doppler (TCD) tech... View more
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