Usefulness of Amino Acid Profiling in Ovarian Cancer Screening with Special Emphasis on Their Role in Cancerogenesis

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Szymon Plewa; Agnieszka Horała; Paweł Dereziński; Agnieszka Klupczynska; Ewa Nowak-Markwitz; Jan Matysiak; Zenon J. Kokot;
  • Publisher: MDPI AG
  • Journal: International Journal of Molecular Sciences,volume 18,issue 12 (issn: 1422-0067, eissn: 1422-0067)
  • Related identifiers: doi: 10.3390/ijms18122727, pmc: PMC5751328
  • Subject: Chemistry | screening | metabolic pathways analysis | ovarian cancer | biomarkers | QD1-999 | amino acids | targeted metabolomics | Article | Biology (General) | QH301-705.5

The aim of this study was to quantitate 42 serum-free amino acids, propose the biochemical explanation of their role in tumor development, and identify new ovarian cancer (OC) biomarkers for potential use in OC screening. The additional value of this work is the schemat... View more
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