Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer’s disease mouse model

Article English OPEN
Chiara Criscuolo ; Veronica Fontebasso ; Silvia Middei ; Martina Stazi ; Martine Ammassari-Teule ; Shirley ShiDu Yan ; Nicola Origlia (2017)
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports, volume 7 (issn: 2045-2322, eissn: 2045-2322)
  • Related identifiers: doi: 10.1038/srep42370, pmc: PMC5304222
  • Subject: Article

The Entorhinal cortex (EC) has been implicated in the early stages of Alzheimer’s disease (AD). In particular, spreading of neuronal dysfunction within the EC-Hippocampal network has been suggested. We have investigated the time course of EC dysfunction in the AD mouse ... View more
Share - Bookmark