Mapping Challenging Mutations by Whole-Genome Sequencing
Harold E. Smith
Amy S. Fabritius
- Publisher: Genetics Society of America
(issn: 2160-1836, eissn: 2160-1836)
bepress|Life Sciences|Biology | QH426-470 | Genetics | variant detection | bepress|Life Sciences|Genetics and Genomics|Genetics | complex alleles | Investigations | forward genetics | SNP mapping
Whole-genome sequencing provides a rapid and powerful method for identifying mutations on a global scale, and has spurred a renewed enthusiasm for classical genetic screens in model organisms. The most commonly characterized category of mutation consists of monogenic, r...