Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging.

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Primiani, Christopher T.; Ryan, Veronica H.; Rao, Jagadeesh S.; Cam, Margaret C.; Ahn, Kwangmi; Modi, Hiren R.; Rapoport, Stanley I.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 9,issue 10 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4203852, doi: 10.1371/journal.pone.0110972
  • Subject: Computational Biology | Research Article | Gene Identification and Analysis | Statistical Analysis of Genetic Association | Bioassays and Physiological Analysis | Gene Regulatory Networks | Genetics | Immune Response | Inflammation | Genome Analysis | Immunology | Biology and Life Sciences | Signal Transduction | Genetic Networks | Developmental Biology | Research and Analysis Methods | Medicine | Organism Development | Microarrays | Q | R | Cell Biology | Cell Signaling | Science | Developmental Signaling | Aging | Medicine and Health Sciences | Genome-Wide Association Studies | Genetic Interactions
    mesheuropmc: sense organs

Background Age changes in expression of inflammatory, synaptic, and neurotrophic genes are not well characterized during human brain development and senescence. Knowing these changes may elucidate structural, metabolic, and functional brain processes over the lifespan, ... View more
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