A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2

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Tobias Wiesenfahrt; Jingjie Duanmu; Frances Snider; Don Moerman; Vinci Au; Erica Li-Leger; Stephane Flibotte; Dylan M. Parker; Craig J. Marshall; Erin Osborne Nishimura; Paul E. Mains; James D. McGhee;
  • Publisher: Genetics Society of America
  • Journal: G3: Genes,volume 8,issue 5,pages1,425-1,437 (issn: 2160-1836, eissn: 2160-1836)
  • Related identifiers: pmc: PMC5940137, doi: 10.1534/g3.118.200079
  • Subject: ELT-2 GATA factor | C. elegans | tasp-1 | QH426-470 | intestine | pqn-82 | Genetics | Mutant Screen Report | taspase | endoderm specification | C . elegans

The ELT-2 GATA factor normally functions in differentiation of the C. elegans endoderm, downstream of endoderm specification. We have previously shown that, if ELT-2 is expressed sufficiently early, it is also able to specify the endoderm and to replace all other member... View more
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