Prognostic significance of CD95, P53, and BCL2 expression in extranodal non-Hodgkin's lymphoma

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Chatzitolios , Anastasios; Venizelos , Ioannis; Tripsiannis , Gregory; Anastassopoulos , George; Papadopoulos , Nikolaos;
(2010)
  • Publisher: Springer Verlag
  • Related identifiers: doi: 10.1007/s00277-010-0945-x
  • Subject: DLBCL | CD95 | Extranodal non-Hodgkin's lymphoma | BCL2 | Prognostic significance | MALTL | P53
    mesheuropmc: hemic and lymphatic diseases | biological phenomena, cell phenomena, and immunity | immune system diseases

International audience; Apoptosis-related proteins play an important role in lymphoma cell death during chemotherapy. In our study, we investigated the prognostic significance of CD95, BCL2, and P53 expression in extranodal non-Hodgkin's lymphoma (NHL). We examined 71 p... View more
  • References (26)
    26 references, page 1 of 3

    1. Feller AC, Diebold J (2004) Histopathology of nodal and extranodal non-Hodgkin's lymphomas. 3rd, completely rev. and updated ed. Springer, Berlin, p 186

    2. Irisarri M, Plumas J, Bonnefoix T et al (2000) Resistance to CD95- mediated apoptosis through constitutive c-FLIP expression in a nonHodgkin's lymphoma B cell line. Leukemia 14:2149-2158

    3. Troeger A, Glouchkova L, Escherich G et al (2008) Reduced expression of defective modulation of TNF receptor/ligand family molecules on proB-ALL blasts. Klin Pediatr 220:353-357

    4. Griffith TS, Yu X, Herndon JM, Green DR, Ferguson TA (1996) CD95-induced apoptosis of lymphocytes in an immune-privileged cite induces immunological tolerance. Immunity 5:7-16

    5. Landowski TH, Moscinski L, Burke R (2001) CD95 antigen mutations in hematopoietic malignancies (review). Leuk Lymphoma 42:835-846

    6. Wilson WH, Teruya-Feldstein J, Fest T (1997) Relationship of P53, BCL2, and tumor proliferation to clinical drug resistance in non-Hodgkin's lymphomas. Blood 89:601-609

    7. Harris SL, Levine AJ (2005) The P53 pathway: positive and negative feedback loops (review). Oncogene 24:2899-2908

    8. Steele RJ, Lane DP (2005) P53 in cancer: a paradigm for modern management of cancer (review). Surg 3:197-205

    9. Kroemer G (1997) The proto-oncogene BCL2 and its role in regulating apoptosis. Nat Med 3:614-620

    10. Chao DT, Korsmeyer SJ (1998) BCL-2 family: regulators of cell death. Annu Rev Immunol 16:395-419

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