Disruption of var2csa gene impairs placental malaria associated adhesion phenotype.

Article English OPEN
Viebig, Nicola K.; Levin, Emily; Dechavanne, Sébastien; Rogerson, Stephen J.; Gysin, Jürg; Smith, Joseph D.; Scherf, Artur; Gamain, Benoit;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 2,issue 9 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0000910, pmc: PMC1975670
  • Subject: Q | R | Research Article | Infectious Diseases/Protozoal Infections | Infectious Diseases/Tropical and Travel-Associated Diseases | Science | Microbiology/Parasitology | Medicine | Microbiology/Cellular Microbiology and Pathogenesis
    mesheuropmc: embryonic structures | parasitic diseases

Infection with Plasmodium falciparum during pregnancy is one of the major causes of malaria related morbidity and mortality in newborn and mothers. The complications of pregnancy-associated malaria result mainly from massive adhesion of Plasmodium falciparum-infected er... View more
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