Leukemia-Initiating Cells in T-Cell Acute Lymphoblastic Leukemia

Article English OPEN
Tan, Shi Hao; Bertulfo, Fatima Carla; Sanda, Takaomi;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Oncology,volume 7 (issn: 2234-943X, eissn: 2234-943X)
  • Related identifiers: doi: 10.3389/fonc.2017.00218, pmc: PMC5627022
  • Subject: T-cell acute lymphoblastic leukemia | TAL1 | Review | leukemia initiating cells | Oncology | NOTCH1 | core regulatory circuit
    mesheuropmc: hemic and lymphatic diseases

T-cell acute lymphoblastic leukemia (T-ALL) is a hematological malignancy characterized by the clonal proliferation of immature T-cell precursors. T-ALL has many similar pathophysiological features to acute myeloid leukemia, which has been extensively studied in the est... View more
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