Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function

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Carola Dewitz; Sofia Pimpinella; Patrick Hackel; Altuna Akalin; Thomas M. Jessell; Niccolò Zampieri;
  • Publisher: Freie Universität Berlin Universitätsbibliothek, Garystr. 39, 14195 Berlin
  • Journal: issn: 2211-1247
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1016/j.celrep.2018.01.059
  • Subject: 612 Human physiology | N-cadherin | 611 Anatomie, Zytologie, Histologie des Menschen | motor pool | 612 Physiologie des Menschen | QH301-705.5 | β-catenin | Cardiovascular and Metabolic Diseases | 611 Human anatomy, cytology, histology | nectins | motor neuron | Technology Platforms | migration | spinal cord | afadin | Function and Dysfunction of the Nervous System | Biology (General)
    • ddc: ddc:612 | ddc:611

Motor neurons in the spinal cord are found grouped in nuclear structures termed pools, whose position is precisely orchestrated during development. Despite the emerging role of pool organization in the assembly of spinal circuits, little is known about the morphogenetic... View more