publication . Article . 2014

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

Yoon S; Lee H; Kim TE; Lee S; Chee DH; Cho JY; Yu KS; Jang IJ;
Open Access English
  • Published: 15 Jan 2014 Journal: Drug Design, Development and Therapy, volume 8, pages 123-128 (issn: 1177-8881, eissn: 1177-8881, Copyright policy)
  • Publisher: Dove Press
Abstract
Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER) formulation with that of the reference immediate-release (IR) formulation in the fasting state. The effect of food on the bioavailability of itopride ER was also assessed....
Subjects
free text keywords: RM1-950, itopride, Therapeutics. Pharmacology, bioavailability, pharmacokinetics, Drug Design, Development and Therapy, Short Report, extended-release, immediate-release
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publication . Article . 2014

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

Yoon S; Lee H; Kim TE; Lee S; Chee DH; Cho JY; Yu KS; Jang IJ;