Enhanced Transmission of Drug-Resistant Parasites to Mosquitoes following Drug Treatment in Rodent Malaria

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Bell, Andrew S. ; Huijben, Silvie ; Paaijmans, Krijn P. ; Sim, Derek G. ; Chan, Brian H. K. ; Nelson, William A. ; Read, Andrew F. (2012)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 7, issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0037172, pmc: PMC3368907
  • Subject: Mosquitoes | Host-Pathogen Interaction | Population Genetics | Animal Models | Research Article | Biology | Anopheles | Microbiology | Medicine | Q | Quantitative Parasitology | Mouse | R | Evolutionary Biology | Genetics | Population Biology | Model Organisms | Vector Biology | Science | Evolutionary Ecology | Immunology | Parasite Evolution | Parasitology
    mesheuropmc: parasitic diseases

The evolution of drug resistant Plasmodium parasites is a major challenge to effective malaria control. In theory, competitive interactions between sensitive parasites and resistant parasites within infections are a major determinant of the rate at which parasite evolut... View more