Enhanced transmission of drug-resistant parasites to mosquitoes following drug treatment in rodent malaria.

Article English OPEN
Bell, Andrew S.; Huijben, Silvie; Paaijmans, Krijn P.; Sim, Derek G.; Chan, Brian H. K.; Nelson, William A.; Read, Andrew F.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 7,issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0037172, pmc: PMC3368907
  • Subject: Mosquitoes | Host-Pathogen Interaction | Population Genetics | Animal Models | Research Article | Biology | Anopheles | Microbiology | Medicine | Quantitative Parasitology | Mouse | Q | R | Evolutionary Biology | Genetics | Population Biology | Model Organisms | Vector Biology | Science | Evolutionary Ecology | Immunology | Parasite Evolution | Parasitology
    mesheuropmc: parasitic diseases

The evolution of drug resistant Plasmodium parasites is a major challenge to effective malaria control. In theory, competitive interactions between sensitive parasites and resistant parasites within infections are a major determinant of the rate at which parasite evolut... View more