Clinical and biochemical profile of lean type 2 diabetes mellitus

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Barma, Punyakrit Deb ; Ranabir, Salam ; Prasad, Lallan ; Singh, Thangjam Premchand (2011)
  • Publisher: Medknow Publications
  • Journal: Indian Journal of Endocrinology and Metabolism, volume 15, issue Suppl1, pages S40-S43 (issn: 2230-8210, eissn: 2230-9500)
  • Related identifiers: doi: 10.4103/2230-8210.83061, pmc: PMC3152194
  • Subject: Diseases of the digestive system. Gastroenterology | microvascular | Original Article | RC648-665 | RC799-869 | Diseases of the endocrine glands. Clinical endocrinology | Lean type diabetesmellitus | macrovasuclar

Background: Type 2 diabetes mellitus is the most prevalent form of diabetes worldwide. In western countries majority of the cases are obese. The scenario may be different in certain parts of India. Various studies have reported a high prevalence of lean type 2 diabetes mellitus with a body mass index < 19 kg/m 2 . Materials and Methods: We evaluated 100 cases of lean type 2 diabetes mellitus (62 males and 38 females). Results and Conclusion: The mean duration of diabetes was 51.7 months (range 5-180 months). The glycemic control was poor according to standard guidelines. The majority of them showed response to oral hypoglycemic agents. Secondary failure to oral hypoglycemic agents was seen in 27 patients. The prevalence of microvascular complications was much higher than macrovascular complications. Neuropathy was the commonest complication seen in 70%, followed by retinopathy in 25%. Only 12 patients had hypertension, one had coronary artery disease and two had cerebrovascular accident. Lipid profile was not significantly deranged in our patients.
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