Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with l-ascorbic acid.

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Wade, KH; Forouhi, NG; Cook, DG; Johnson, P; McConnachie, A; Morris, RW; Rodriguez, S; Ye, Z; Ebrahim, S; Padmanabhan, S; Watt, G; Bruckdorfer, KR; Wareham, NJ; Whincup, PH; Chanock, S; Sattar, N; Lawlor, DA; Davey Smith, G; Timpson, NJ;

Background: Observational studies showed that circulating l-ascorbic acid (vitamin C) is inversely associated with cardiometabolic traits. However, these studies were susceptible to confounding and reverse causation.\ud \ud Objectives:We assessed the relation between l-... View more
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