Development of a Pseudomonas aeruginosa Agmatine Biosensor

Article, Other literature type English OPEN
Gilbertsen, Adam; Williams, Bryan;

Agmatine, decarboxylated arginine, is an important intermediary in polyamine production for many prokaryotes, but serves higher functions in eukaryotes such as nitric oxide inhibition and roles in neurotransmission. Pseudomonas aeruginosa relies on the arginine decarbox... View more
  • References (28)
    28 references, page 1 of 3

    Wortham, B.W.; Patel, C.N.; Oliveira, M.A. Polyamines in bacteria: Pleiotropic effects yet specific mechanisms. Adv. Exp. Med. Biol. 2007, 603, 106-115.

    Gugliucci, A. Polyamines as clinical laboratory tools. Clin. Chim. Acta 2004, 344, 23-35.

    Piletz, J.E.; Aricioglu, F.; Cheng, J.T.; Fairbanks, C.A.; Gilad, V.H.; Haenisch, B.; Halaris, A.; Hong, S.; Lee, J.E.; Li, J.; et al. Agmatine: Clinical applications after 100 years in translation.

    Drug Discov. Today 2013, 18, 880-893.

    4. Wade, C.L.; Eskridge, L.L.; Nguyen, H.O.; Kitto, K.F.; Stone, L.S.; Wilcox, G.; Fairbanks, C.A. Immunoneutralization of agmatine sensitizes mice to micro-opioid receptor tolerance. J. Pharmacol. Exp. Ther. 2009, 331, 539-546.

    5. Reis, D.J.; Regunathan, S. Agmatine: An endogenous ligand at imidazoline receptors is a novel neurotransmitter. Ann. N. Y. Acad. Sci. 1999, 881, 65-80.

    6. Regunathan, S.; Piletz, J.E. Regulation of inducible nitric oxide synthase and agmatine synthesis in macrophages and astrocytes. Ann. N. Y. Acad. Sci. 2003, 1009, 20-29.

    7. Mun, C.H.; Lee, W.T.; Park, K.A.; Lee, J.E. Regulation of endothelial nitric oxide synthase by agmatine after transient global cerebral ischemia in rat brain. Anat. Cell Biol. 2010, 43, 230-240.

    8. Janowitz, T.; Kneifel, H.; Piotrowski, M. Identification and characterization of plant agmatine iminohydrolase, the last missing link in polyamine biosynthesis of plants. FEBS Lett. 2003, 544, 258-261.

    9. Jubault, M.; Hamon, C.; Gravot, A.; Lariagon, C.; Delourme, R.; Bouchereau, A.; Manzanares-Dauleux, M.J. Differential regulation of root arginine catabolism and polyamine metabolism in clubroot-susceptible and partially resistant Arabidopsis genotypes. Plant Physiol. 2008, 146, 2008-2019.

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