Penicillin-resistant viridans streptococci have obtained altered penicillin-binding protein genes from penicillin-resistant strains of Streptococcus pneumoniae.

Other literature type, Article English OPEN
DOWSON, CG; HUTCHISON, A; WOODFORD, N; JOHNSON, AP; GEORGE, RC; SPRATT, BG;
(1990)
  • Publisher: National Academy of Sciences
  • Related identifiers: pmc: PMC54428, doi: 10.1073/pnas.87.15.5858
  • Subject: Bacterial Proteins | Research Article | Penicillin Resistance | MULTIDISCIPLINARY SCIENCES | Molecular Sequence Data | Nucleic Acid Hybridization | Hexosyltransferases | Oligonucleotide Probes | Amino Acid Sequence | Muramoylpentapeptide Carboxypeptidase | Mosaicism | Science & Technology - Other Topics | Base Sequence | Peptidyl Transferases | Polymerase Chain Reaction | MD Multidisciplinary | Glycogen Debranching Enzyme System | Species Specificity | Genes, Bacterial | Aminoacyltransferases | DNA, Bacterial | Carrier Proteins | Penicillin-Binding Proteins | Streptococcus | Science & Technology | Penicillins | Streptococcus pneumoniae
    mesheuropmc: polycyclic compounds

Penicillin-resistant strains of Streptococcus pneumoniae possess altered forms of penicillin-binding proteins (PBPs) with decreased affinity for penicillin. The PBP2B genes of these strains have a mosaic structure, consisting of regions that are very similar to those in... View more
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