Molecular analysis of the interaction between Clostridium perfringens Enterotoxin and Claudins

Doctoral thesis German OPEN
Protze, Jonas;
(2015)
  • Publisher: Freie Universität Berlin Universitätsbibliothek, Garystr. 39, 14195 Berlin
  • Subject: Protein–protein interactions | Structure–function study | Membrane proteins | Molecular modeling | 572 Biochemistry | 570 Life sciences | Tight junctions | Mutagenesis | 570 Biowissenschaften; Biologie | 572 Biochemie
    • ddc: ddc:570 | ddc:572

Claudins are essential constituents of Tight Junctions (TJs) and responsible for maintenance of these cell-cell contacts. Binding of <i>Clostridium perfringens</i> Enterotoxin’s C-terminal domain (cCPE) to the extracellular loop 2 (EZS2) of claudins, especially Cld3, Cl... View more
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