A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast.

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Sishuo Cao ; Wentao Xu ; Nan Zhang ; Yan Wang ; YunBo Luo ; Xiaoyun He ; Kunlun Huang
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 7, issue 3 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3293924, doi: 10.1371/journal.pone.0032943
  • Subject: Signaling in Cellular Processes | Chemistry | Signaling Cascades | Research Article | Biology | Molecular Cell Biology | Proteomics | Signal Transduction | Microbiology | Medicine | Q | R | Model Organisms | Biochemistry | Science | Yeast and Fungal Models | Metabolism | Mycology | Phytochemistry
    mesheuropmc: sense organs

Grapefruit seed extract (GSE), which has powerful anti-fungal activity, can induce apoptosis in S. cerevisiae. The yeast cells underwent apoptosis as determined by testing for apoptotic markers of DNA cleavage and typical chromatin condensation by Terminal Deoxynucleoti... View more
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