Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation

Other literature type, Article English OPEN
Mahdavi, Jafar; Sondén, Berit; Hurtig, Marina; Olfat, Farzad O.; Forsberg, Lina; Roche, Niamh; Ångström, Jonas; Larsson, Thomas; Teneberg, Susann; Karlsson, Karl-Anders; Altraja, Siiri; Wadström, Torkel; Kersulyte, Dangeruta; Berg, Douglas E.; Dubois, Andre; Petersson, Christoffer; Magnusson, Karl-Eric; Norberg, Thomas; Lindh, Frank; Lundskog, Bertil B.; Arnqvist, Anna; Hammarström, Lennart; Borén, Thomas;

Helicobacter pylori adherence in the human gastric mucosa involves specific bacterial adhesins and cognate host receptors. Here, we identify sialyl-dimeric-Lewis × glycosphingolipid as a receptor for H. pylori and show that H. pylori infection induced formation of sialy... View more
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