publication . Article . 2018

The Effects of Chinese Herbal Medicines on the Quorum Sensing-Regulated Virulence in Pseudomonas aeruginosa PAO1

Yee Meng Chong; Kah Yan How; Wai Fong Yin; Kok Gan Chan;
Open Access English
  • Published: 01 Apr 2018 Journal: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry, volume 23, issue 4 (issn: 1420-3049, eissn: 1420-3049, Copyright policy)
  • Publisher: MDPI
Abstract
The quorum sensing (QS) system has been used by many opportunistic pathogenic bacteria to coordinate their virulence determinants in relation to cell-population density. As antibiotic-resistant bacteria are on the rise, interference with QS has been regarded as a novel way to control bacterial infections. As such, many plant-based natural products have been widely explored for their therapeutic roles. These natural products may contain anti-QS compounds that could block QS signals generation or transmission to combat QS pathogens. In this study, we report the anti-QS activities of four different Chinese herbal plant extracts: Poria cum Radix pini, Angelica dahur...
Subjects
mesheuropmc: food and beverages
free text keywords: Angelica dahurica, natural products, quorum sensing, Organic chemistry, QD241-441, Rhizoma cibotii, Pseudomonas aeruginosa PAO1, Poria cum Radix pini, Article, Schizonepeta tenuifolia
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publication . Article . 2018

The Effects of Chinese Herbal Medicines on the Quorum Sensing-Regulated Virulence in Pseudomonas aeruginosa PAO1

Yee Meng Chong; Kah Yan How; Wai Fong Yin; Kok Gan Chan;