Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

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Storm, Janet; Perner, Jan; Aparicio, Isabela; Patzewitz, Eva-Maria; Olszewski, Kellen; Llinas, Manuel; Engel, Paul C.; Mueller, Sylke;

<p>Abstract</p> <p>Background</p> <p><it>Plasmodium falciparum </it>contains three genes encoding potential glutamate dehydrogenases. The protein encoded by <it>gdha </it>has previously been biochemically and structurally characterized. It was suggested that it is impor... View more