The Kynurenine Pathway: a Proposed Mechanism Linking Diabetes and Periodontal Disease in Diabetic Patients

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Rishabh Kapila; K S Nagesh; Asha R Iyengar; Subash BV Adiga;
(2011)
  • Publisher: Wolters Kluwer Medknow Publications
  • Journal: Dental Hypotheses (issn: 2155-8213, eissn: 2155-8213)
  • Publisher copyright policies & self-archiving
  • Subject: RK1-715 | Dentistry | Kynurenine. | Diabetes | Periodontal Disease | Tryptophan

Introduction: Diabetes mellitus is a metabolic disease characte-rized by dysregulation of carbohydrate, protein and lipid metabolism. Diabetes could result, in part, in activation of tryptophan metabolism. Diabetic patients are more susceptible to gingivitis and periodo... View more
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