publication . Other literature type . Article . 2008

Prevalence of β-Thalassemia Trait and Glucose-6-Phosphate Dehydrogenase Deficiency in Iranian Jews

Majid Yavarian; Eliezer A. Rachmilewitz; Abdolreza Afrasiabi; Mehran Karimi; Javad Dehbozorgian;
  • Published: 01 Feb 2008
  • Publisher: Elsevier BV
Background β-thalassemia is the most common inherited single gene disorder worldwide, and glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme deficiency. The goal of this study was to compare the frequency of β-thalassemia trait and G6PD among the Moslem and Jewish populations in Shiraz, southern Iran. Methods We examined 201 Moslems and 187 Jewish subjects who were selected by random sampling. For diagnosis of thalassemia, complete blood count and hemoglobin electrophoresis were carried out and for G6PD deficiency, fluorescent spot test methods were used as a screening test. Results Among Moslem subjects, 14 cases (7.0%) were dia...
Medical Subject Headings: congenital, hereditary, and neonatal diseases and abnormalitieshemic and lymphatic diseases
free text keywords: General Medicine, Screening test, Hemoglobin electrophoresis, Glucose-6-phosphate dehydrogenase deficiency, medicine.disease, medicine, Thalassemia, Southern Iran, Enzyme deficiency, Genetics, Physiology, β thalassemia trait, Complete blood count, medicine.diagnostic_test, business.industry, business
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