A reductive aminase from Aspergillus oryzae

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Aleku, Godwin; France, Scott; Man, Henry Wing-Hong; Mangas-Sanchez, Juan; Montgomery, Sarah L; Sharma, Mahima; Leipold, Friedemann; Hussain, Shahed; Grogan, Gideon James; Turner, Nicholas;
(2017)

Reductive amination is one of the most important methods for the synthesis of chiral amines. Here we report the discovery of an NADP(H)-dependent reductive aminase from Aspergillus oryzae (AspRedAm, Uniprot code Q2TW47) which can catalyse the reductive coupling of a bro... View more
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