Variants of the EAAT2 glutamate transporter gene promoter are associated with cerebral palsy in preterm Infants

Article English OPEN
Varadi, A.;
  • Publisher:

Abstract Pretermdelivery is associatedwith neurodevelopmental\ud impairment caused by environmental and genetic factors.\ud Dysfunction of the excitatory amino acid transporter 2\ud (EAAT2) and the resultant impaired glutamate uptake can lead to neurological disorders. ... View more
  • References (53)
    53 references, page 1 of 6

    1. Field DJ, Dorling JS, Manktelow BN, Draper ES (2008) Survival of extremely premature babies in a geographically defined population: prospective cohort study of 1994-9 compared with 2000-5. Br Med J 336:1221-1223. doi:10.1136/bmj.39555.670718.BE

    2. Costeloe KL, Hennessy EM, Haider S, Stacey F, Marlow N, Draper ES (2012) Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies). Br Med J 345:e7976. doi:10.1136/bmj.e7976

    3. Galinsky R, Polglase GR, Hooper SB, Black MJ, Moss TJ (2013) The consequences of chorioamnionitis: preterm birth and effects on development. J Pregnancy 2013:412831. doi:10.1155/2013/ 412831

    4. Moser K, Macfarlane A, Chow YH, Hilder L, Dattani N (2007) Introducing new data on gestation-specific infant mortality among babies born in 2005 in England and Wales. Health Stat Q 2007 Autumn:13-27.

    5. Wilson-Costello D, Friedman H, Minich N, Siner B, Taylor G, Schluchter M, Hack M (2007) Improved neurodevelopmental outcomes for extremely low birth weight infants in 2000-2002. Pediatrics 119:37-45. doi:10.1542/peds.2006-1416

    6. Mangham LJ, Petrou S, Doyle LW, Draper ES, Marlow N (2009) The cost of preterm birth throughout childhood in England and Wales. Pediatrics 123:e312-e327. doi:10.1542/peds.2008-1827

    7. Marret S, Marchand-Martin L, Picaud J-C, Mascoët J-M, Arnaud C, Rozé JC, Truffert P, Larroque B et al, EPIPAGE Study Group (2013) Brain injury in very preterm children and neurosensory and cognitive disabilities during childhood: the EPIPAGE cohort study. PLoS One 8:e62683. doi:10.1371/journal.pone.0062683

    8. Boardman JP, Waley A, Ball G, Takousis P, Krishnan ML, HughesCarre L, Aljabar P, Serag A et al (2014) Common genetic variants and risk of brain injury after preterm birth. Pediatrics 133:e1655- e1663. doi:10.1542/peds.2013-3011

    9. Volpe JJ (2009) The encephalopathy of prematurity-brain injury and impaired brain development inextricably intertwined. Semin. Pediatr Neurol 16:167-178. doi:10.1016/j.spen.2009.09.005

    10. Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA (2011) The developing oligodendrocyte: key cellular target in brain injury in the premature infant. Int J Devl Neurosci 29:423-440. doi:10.1016/j. ijdevneu.2011.02.012

  • Related Organizations (4)
  • Metrics
Share - Bookmark