Lifespan pigmentation changes of the substantia nigra detected by neuromelanin-sensitive MRI

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Xing, Yue.; Sapuan, Abdul.; Dineen, Rob.; Auer, Dorothee P..;
  • Publisher: Wiley
  • Subject: Biomedical Research Centre | Beacon - Precision Imaging

Background: Neuromelanin is a pigment with strong iron-chelating properties preferentially found in dopaminergic neurons of the substantia nigra, pars compacta (SNpc). Parkinson's disease is characterized by pronounced, MRI detectable neuromelanin loss, but the neuropro... View more
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