Differential Regulation of GABABReceptor Trafficking by Different Modes ofN-methyl-d-aspartate (NMDA) Receptor Signaling

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Kantamneni, Sriharsha; Gonzàlez-Gonzàlez, Inma; Luo, Jia; Cimarosti, Helena; Jacobs, Susan C.; Jaafari, Nadia; Henley, Jeremy M.;
  • Publisher: The American Society for Biochemistry and Molecular Biology,
  • Identifiers: doi: 10.1074/jbc.M113.487348
  • Subject: B200
    mesheuropmc: nervous system

Inhibitory GABAB receptors (GABABRs) can down-regulate most excitatory synapses in the CNS by reducing postsynaptic excitability. Functional GABABRs are heterodimers of GABAB1 and GABAB2 subunits and here we show that the trafficking and surface expression of GABABRs is... View more
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