publication . Article . 2004

Are there functional consequences of a reduction in selenium intake in UK subjects?

Jackson, Malcolm J; Dillon, Stephanie; Broome, Caroline S; McArdle, Anne; Hart, C Anthony; McArdle, Francis;
Open Access
  • Published: 01 Nov 2004 Journal: Proceedings of the Nutrition Society, volume 63, pages 513-517 (issn: 0029-6651, eissn: 1475-2719, Copyright policy)
  • Publisher: Cambridge University Press (CUP)
  • Country: United Kingdom
Abstract
<jats:p>Dietary Se levels in the UK have fallen over the last 20 years and recent surveys indicate that average Se intakes are 30–40 μg/d, which is well below the current UK reference nutrient intake for adult men (75 μg/d) or women (60 μg/d). Functional consequences of this decline have not been recognised, although epidemiological data suggest it may contribute to increased risk of infections and incidence of some cancers. Previous data have indicated that biochemical changes in Se-dependent proteins occur in otherwise healthy UK subjects given small Se supplements. The current studies have focused on the effect of small Se supplements on the immune response s...
Subjects
free text keywords: Nutrition and Dietetics, Medicine (miscellaneous), Immune system, Poliovirus, medicine.disease_cause, medicine, Epidemiology, medicine.medical_specialty, Selenium intake, Genetic variability, Viral replication, Attenuated vaccine, Immunology, business.industry, business
Related Organizations
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