Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo

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Richardson, Simon C. W.; Pattrick, Nicola G.; Lavignac, Nathalie; Ferruti, Paolo; Duncan, Ruth;

Linear poly(amidoamine)s (PAAs) have been designed to exhibit minimal non-specific toxicity, display pH-dependent membrane lysis and deliver genes and toxins in vitro. The aim of this study was to measure PAA cellular uptake using ISA1-OG (and as a reference ISA23-OG) i... View more
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