Persistent isolated hypocortisolism following brief treatment with trilostane

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Ramsey, I.K.; Richardson, J.; Lenard, Z.; Tebb, A.J.; Irwin, P.J.;
(2008)
  • Publisher: Wiley-Blackwell
  • Subject: SF600

A 12-year-old male neutered Miniature Poodle with confirmed pituitary-dependent hyperadrenocorticism was treated with trilostane. After three doses, it developed clinical and laboratory changes suggestive of isolated hypocortisolism ('atypical hypoadrenocorticism'), whi... View more
  • References (20)
    20 references, page 1 of 2

    1. Neiger R, Ramsey I, O'Connor J, Hurley KJ, Mooney CT. Trilostane treatment of 78 dogs with pituitary-dependent hyperadrenocorticism. Vet Rec 2002; 150:799-804.

    2. Ruckstuhl NS, Nett CS, Reusch CE. Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane. Am J Vet Res 2002; 63:506-512.

    3. Braddock JA, Church DB, Robertson ID, Watson AD. Trilostane treatment in dogs with pituitary-dependent hyperadrenocorticism. Aust Vet J. 2003; 81:600-7

    4. Wenger M, Sieber-Ruckstuhl NS, Muller C, Reusch CE. Effect of trilostane on serum concentrations of aldosterone, cortisol, and potassium in dogs with pituitarydependent hyperadrenocorticism Am J Vet Res 2004; 65:1245-50.

    5. Barker E, Campbell S, Tebb A, et al. A comparison of the survival times of dogs treated for hyperadrenocorticism with trilostane or mitotane J Vet Intern Med 2005; 19:810-815

    6. Kintzer PP, Peterson ME. Mitotane (o,p'-DDD) treatment of 200 dogs with pituitary-dependent hyperadrenocorticism. J Vet Intern Med 1991; 5:182-190.

    7. Dunn KJ, Herrtage ME, Dunn JK. Use of ACTH stimulation tests to monitor the treatment of canine hyperadrenocorticism. Vet Rec 1995; 137: 161-165

    8. Chapman PS, Kelly DF, Archer J, Brockman DJ, Neiger R. Adrenal necrosis in a dog receiving trilostane for the treatment of hyperadrenocorticism. J Small Anim Pract. 2004; 45:307-10

    9. Hoffman KL Ultrasonographic examination in canine hyperadrenocorticism Aust Vet J 2003; 81: 27-30

    10. Russell NJ, Foster S, Clark P, Robertson ID, Lewis D, Irwin PJ. Comparison of radioimmunoassay and chemiluminescent assay methods to estimate canine blood cortisol concentrations Aust Vet J 2007; 85: 487-494

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