Self-assembled arginine-capped peptide bolaamphiphile nanosheets for cell culture and controlled wettability surfaces

Article English OPEN
da Silva, Emerson Rodrigo; Walter, Merlin Nathaniel Mark; Reza, Mehedi; Castelletto, Valeria; Ruokolainen, Janne; Connon, Che John; Alves, Wendel Andrade; Hamley, Ian William;

The spontaneous assembly of a peptide bolaamphiphile in water, namely, RFL4FR (R, arginine; F, phenylalanine; L, leucine) is investigated, along with its novel properties in surface modification and usage as substrates for cell culture. RFL4FR self-assembles into nanosh... View more
  • References (75)
    75 references, page 1 of 8

    (1) de la Rica, R.; Matsui, H. Applications of Peptide and ProteinBased Materials in Bionanotechnology. Chem. Soc. Rev. 2010, 39, 3499−3509.

    (2) Hamley, I. W. Self-Assembly of Amphiphilic Peptides. Soft Matter 2011, 7, 4122−4138.

    (3) Reches, M.; Gazit, E. Molecular Self-Assembly of Peptide Nanostructures: Mechanism of Association and Potential Uses. Curr.

    Nanosci. 2006, 2, 105−111.

    (4) Binder, H.; Lindblom, G. Charge-Dependent Translocation of the Trojan Peptide Penetratin Across Lipid Membranes. Biophys. J.

    (5) Pierschbacher, M. D.; Ruoslahti, E. Cell Attachment Activity of Fibronectin can be Duplicated by Small Synthetic Fragments of the Molecule. Nature 1984, 309, 30−33.

    (6) Gouveia, R. M.; Castelletto, V.; Hamley, I. W.; Connon, C. J.

    New Self-Assembling Multifunctional Templates for the Biofabrication and Controlled Self-Release of Cultured Tissue. Tissue Eng., Part A 2015, 21, 1772−1784.

    (7) Zasloff, M. Antimicrobial Peptides of Multicellular Organisms.

    Nature 2002, 415 (6870), 389−395.

  • Metrics
Share - Bookmark