Design, synthesis and biological evaluation of potential antibacterial oligonucleotides

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Traube, Andrew;

Purine and pyrimidine triplex-forming oligonucleotides (TFOs), as potential antibacterial agents, were designed to bind by Hoogsteen and reverse Hoogsteen hydrogen bonds in a sequence specific manner in the major groove of genomic DNA at specific polypurine sites within... View more
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