Fully Atomistic Simulations of Protein Unfolding in Low Speed Atomic Force Microscope and Force Clamp Experiments with the Help of Boxed Molecular Dynamics

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Booth, JJ; Shalashilin, DV;
  • Publisher: American Chemical Society
  • Subject:
    arxiv: Quantitative Biology::Biomolecules
    mesheuropmc: biological sciences

The results of Boxed Dynamics (BXD) fully atomistic simulations of protein unfolding by Atomic Force Microscope (AFM), in both force clamp (FC) and velocity clamp (VC) modes are reported. In AFM experiments the unfolding occurs on time scale which is too long for standa... View more
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