publication . Article . 2015

Symptoms of prenatal depression are associated with raised salivary alpha-amylase levels.

Elizabeth C. Braithwaite; Paul G. Ramchandani; Tracy A. Lane; Susannah E. Murphy;
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  • Published: 28 Jun 2015 Journal: Psychoneuroendocrinology, volume 60, pages 163-172 (issn: 0306-4530, Copyright policy)
  • Publisher: Elsevier BV
  • Country: United Kingdom
Abstract
Abstract Purpose Prenatal depression increases risk for a number of adverse offspring outcomes, however the biological mechanisms underlying this association remain unclear. It has been suggested that maternal glucocorticoids may mediate this link, though supporting evidence has been mixed. An alternative mechanism of effect may be via depression-induced changes in maternal sympathetic nervous system (SNS) function. We examined this hypothesis by determining the relationship between symptoms of maternal prenatal depression and diurnal salivary alpha-amylase (sAA) levels. Methods 76 pregnant women were recruited during either the second or third trimester of preg...
Subjects
free text keywords: Biological Psychiatry, Endocrinology, Diabetes and Metabolism, Endocrinology, Endocrine and Autonomic Systems, Psychiatry and Mental health, Sympathetic nervous system, medicine.anatomical_structure, medicine, Pregnancy, medicine.disease, Internal medicine, medicine.medical_specialty, Offspring, Edinburgh Postnatal Depression Scale, Diabetes mellitus, Fetus, Young adult, Saliva, Psychology
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