Polymorphism in glutathione S-transferase P1 is\ud associated with susceptibility to chemotherapyinduced\ud leukemia

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Allan, J.M.; Wild, C.P.; Rollinson, S.; Willett, E.V.; Moorman, A.V.; Dovey, G.J.; Roddam, P.L.; Roman, E.; Cartwright, R.A.; Morgan, G.J.;
(2001)
  • Subject:
    mesheuropmc: hemic and lymphatic diseases | neoplasms

Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens. Functional polymorphisms exist in at least three genes that en... View more
  • References (58)
    58 references, page 1 of 6

    1. Kaldor, J. M., Day, N. E., Clarke, E. A., Van Leeuwen, F. E., Henryamar, M., Fiorentino, M. V., Bell, J., Pedersen, D., Band, P., Assouline, D., et al. (1990) N. Engl. J. Med. 322, 7-13.

    2. Kaldor, J. M., Day, N. E., Pettersson, F., Clarke, E. A., Pedersen, D., Mehnert, W., Bell, J., Host, H., Prior, P., Karjalainen, S., et al. (1990) N. Engl. J. Med. 322, 1-6.

    3. Travis, L. B., Curtis, R. E., Boice, J. D., Platz, C. E., Hankey, B. F. & Fraumeni, J. F. (1996) Cancer Res. 56, 1564-1570.

    4. Travis, L. B., Holowaty, E. J., Bergfeldt, K., Lynch, C. F., Kohler, B. A., Wiklund, T., Curtis, R. E., Hall, P., Andersson, M., Pukkala, E., et al. (1999) N. Engl. J. Med. 340, 351-357.

    5. Travis, L. B., Andersson, M., Gospodarowicz, M., van Leeuwen, F. E., Bergfeldt, K., Lynch, C. F., Curtis, R. E., Kohler, B. A., Wiklund, T., Storm, H., et al. (2000) J. Natl. Cancer Inst. 92, 1165-1171.

    6. Woldon, S. L., Lamborn, K. R., Cleary, S. F., Tate, D. J. & Donaldson, S. S. (1998) J. Clin. Oncol. 16, 536-544.

    7. Diamandidou, E., Buzdar, A. U., Smith, T. L., Frye, D., Witjaksono, M. & Hortobagyi, G. N. (1996) J. Clin. Oncol. 14, 2722-2730.

    8. Greene, M. H., Harris, E. L., Gershenson, D. M., Malkasian, G. D., Jr., Melton, L. J., III, Dembo, A. J., Bennett, J. M., Moloney, W. C. & Boice, J. D., Jr. (1986) Ann. Intern. Med. 105, 360-367.

    9. Fisher, B., Rockette, H., Fisher, E. R., Wickerman, D. L., Redmond, C. & Brown, A. (1985) J. Clin. Oncol. 3, 1640-1658.

    10. Brusamolino, E., Anselmo, A. P., Klersy, C., Santoro, M., Orlandi, E., Pagnucco, G., Lunghi, F., Maurice-Enrici, R., Baroni, C. D., Lazzarino, M., et al. (1998) Haematologica 83, 812-823.

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