publication . Other literature type . Article . 2016

Antioxidant and Antiproliferative Properties of the Essential Oils of Satureja thymbra and Satureja parnassica and their Major Constituents

  • Published: 01 Nov 2016
  • Publisher: Anticancer Research USA Inc.
  • Country: United Kingdom
Aim: The biopotential of the essential oils of the Greek aromatic plants Satureja thymbra and Satureja parnassica were investigated, together with their major components carvacrol, thymol, γ-terpinene and p-cymene. \ud \ud Materials and Methods: Antioxidant and cancer cell cytotoxic properties were determined using 2,2-diphenyl-1-picrylhydrazyl and sulforhodamine B assays, respectively. The antiproliferative potential was studied against the MCF-7, A549, HepG2 and Hep3B cell lines. \ud \ud Results: S. thymbra oil possessed stronger antioxidant and antiproliferative capacity when tested on MCF-7 cells compared to S. parnassica oil. Thymol exhibited two-fold great...
free text keywords: B300, C900, Antioxidant, medicine.medical_treatment, medicine, A549 cell, Potency, Carvacrol, chemistry.chemical_compound, chemistry, Sulforhodamine B, Biochemistry, Satureja parnassica, Thymbra, food.ingredient, food, Biology, Thymol
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17 references, page 1 of 2

1 Edris A. E: Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res 21(4): 308-323, 2007. [OpenAIRE]

2 Bakkali F, Averbeck S, Averbeck, D and Idaomar M: Biological effects of essential oils-a review. Food Chem Toxicol 46(2): 446-475, 2008.

3 Chorianopoulos N, Kalpoutzakis E, Aligiannis N, Mitaku S, Nychas GJ and Haroutounian SA: Essential oils of Satureja, Origanum, and Thymus species: chemical composition and antibacterial activities against foodborne pathogens. J Agric Food Chem 52(26): 8261-8267, 2004. [OpenAIRE]

4 Chorianopoulos N, Evergetis E, Mallouchos A, Kalpoutzakis E, Nychas GJ and Haroutounian SA: Characterization of the essential oil volatiles of Satureja thymbra and Satureja parnassica: Influence of harvesting time and antimicrobial activity. J Agric Food Chem 54(8): 3139-3145, 2006. [OpenAIRE]

5 Michaelakis A, Theotokatos SA, Koliopoulos G and Chorianopoulos NG: Essential oils of satureja species: insecticidal effect on Culex pipiens larvae (Diptera: Culicidae). Molecules 12(12): 2567-2578, 2007. [OpenAIRE]

6 Loizzo MR, Saab AM, Tundis R, Statti GA, Menichini F, Lampronti I, Gambari R, Cinatl J and Doerr HW: Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chem Biodivers 5(3): 461-470, 2008. [OpenAIRE]

7 Ayvaz A, Sagdic O, Karaborklu S and Ozturk I: Insecticidal activity of the essential oils from different plants against three stored-product insects. J Insect Sci 10, 21, 2010.

8 Giweli A, Džamić AM, Soković M, Ristić MS and Marin PD: Antimicrobial and antioxidant activities of essential oils of Satureja thymbra growing wild in Libya. Molecules 17(5): 4836-4850, 2012. [OpenAIRE]

9 Loizzo MR, Tundis R, Menichini F, Saab AM, Statti GA and Menichini F: Cytotoxic activity of essential oils from Labiatae and Lauraceae families against in vitro human tumor models. Anticancer Res 27(5A): 3293-3299, 2007. [OpenAIRE]

33 Jaafari A, Tilaoui M, Mouse HA, M'bark LA, Aboufatima R, Chait A, Lepoivre M and Zyad A: Comparative study of the antitumor effect of natural monoterpenes: relationship to cell cycle analysis. Rev Bras Farmacogn 22(3): 534-540, 2012. [OpenAIRE]

34 Mehdi SJ, Ahmad A, Irshad M, Manzoor N and Rizvi MMA: Cytotoxic effect of Carvacrol on human cervical cancer cells. Biology and Medicine, 3(2): 307-312, 2011.

35 Karkabounas S, Kostoula O, Daskalou T, Veltsistas P, Karamouzis M, Zelovitis I, Metsios A, Lekkas P, Evangelou AM, Kotsis N and Skoufos, I: Anticarcinogenic and antiplatelet effects of carvacrol. Exp Oncol 28(2): 121-125, 2006.

36 Aydın E, Türkez H and Keleş MS: The effect of carvacrol on healthy neurons and N2a cancer cells: some biochemical, anticancerogenicity and genotoxicity studies. Cytotechnology 66(1): 149-157, 2014.

37 Ferraz RP, Bomfim DS, Carvalho NC, Soares MB, da Silva TB, Machado WJ, Prata AP, Costa EV, Moraes VR, Nogueira PC and Bezerra DP: Cytotoxic effect of leaf essential oil of Lippia gracilis Schauer (Verbenaceae). Phytomedicine 20(7): 615-21, 2013.

38 Deb DD, Parimala G, Saravana Devi S and Chakraborty T: Effect of thymol on peripheral blood mononuclear cell PBMC and acute promyelotic cancer cell line HL-60. Chem Biol Interact 193(1): 97-106, 2011.

17 references, page 1 of 2
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