The minor house dust mite allergen Der p 13 is a fatty acid binding protein and an activator of a TLR2-mediated innate immune response

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Satitsuksanoa, Pattraporn; Kennedy, Malcolm; Gilis, Dimitri; Le Mignon, Maxime; Suratannon, Narissara; Soh, Wai Tuck; Wongpiyabovorn, Jongkonnee; Chatchatee, Pantipa; Vangveravong, Mukda; Rerkpattanapipat, Ticha; Sangasapaviliya, Atik; Piboonpocanun, Surapon; Nony, Emmanuel; Ruxrungtham, Kiat; Jacquet, Alain;
  • Publisher: Wiley

Background: The house dust mite (HDM) allergen Der p 13 could be a lipid-binding protein able to activate key innate signaling pathways in the initiation of the allergic response. We investigated the IgE reactivity of recombinant Der p 13 (rDer p 13), its lipid binding ... View more
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